Hyperglycemia is a key factor leading to hepatic complications in diabetes, and the ability of Vinca rosea to lower blood glucose suggests it may improve glucose metabolism, enhance insulin sensitivity, or reduce oxidative stress, which has been a focal point in recent antidiabetic research from Singh et al. (2013) [16], Gadewar et al. (2023) [17]. Here, INS is linked to Hyperglycemia.