Several societies, including the European Society of Cardiology/European Society of Hypertension (ESC/ESH) and International Society for Hypertension (ISH), and Indian guidelines on hypertension-IV (2019) have recommended the use of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers (ARBs) as a first-line therapy for treating hypertension [16-18]. Here, ACE is linked to Hypertension.