Similar to the findings reported by Ma S et al. [13], who observed an AUC of 0.825 (95% CI: 0.722-0.929) for Lp-PLA2 in the acute coronary syndrome (ACS) group, we found that Lp-PLA2 exhibited an AUC of 0.935 (95% CI: 0.84-0.98), with a sensitivity of 88.2% and specificity of 90.9% at a cutoff value of >392 ng/ml in homozygous variant carriers. Here, PLA2G7 is linked to acute coronary syndrome.