Compared by ANOVA or Kruskall Wallis test, *significantly different from control group by Tukey test (p < 0.05) or Mann Whitney test; Abbreviations: DLBCL, diffuse large B- cell lymphoma, CTSS, cathepsin S; Cys C, cystatin C; LDH, lactate dehydrogenase. This evidence concerns the gene CST3 and diffuse large B-cell lymphoma.