Additionally, these fractions reduce the levels of hydroxyproline and collagen in liver tissue, as well as liver fibrosis indicators such as hyaluronic acid, type III procollagen, type IV collagen, and laminin in rats with liver fibrosis (He et al., 2012; Wang et al., 2013a; Wang et al., 2013b). The gene discussed is LAMB2; the disease is Hepatic fibrosis.