In the validation dataset of NSCLC, the AUCs of COL1A1, CEBPA, PLAU, JUNB, JUN, TGFBR2, FOS, and EZH2 were 0.946, 0.794, 0.725, 0.836, 0.859, 0.985, 0.862, and 0.905, respectively. Here, EZH2 is linked to non-small cell lung carcinoma.