Studies have linked COL1A1 to the formation of arterial dissection (Zekavat et al., 2022), which may explain the association between AMI and COL1A1. Some studies have also pointed out that type I collagen’s effective deposition is crucial for the healing process after MI (Nong et al., 2011). This evidence concerns the gene COL1A1 and myocardial infarction.