When comparing sepsis and CINS subgroups, however, we noted that temporal increases in mHLA-DR were primarily driven by the CINS subset of patients, while the septic subset drove increases in ALC, LPS-induced TNF and IL-6 (whether normalized to monocyte count or not), and PMA-induced IFNg in the overall cohort. The gene discussed is IFNG; the disease is Sepsis.