Baseline data analysis revealed that several key indicators, including DBP, atrial fibrillation incidents, NIHSS score, d-D, hs-CRP, NLR, SIRI, SII, NT-proBNP, as well as the S100-β, were significantly elevated in the POCD group compared to the non-POCD group (Table 1). The gene discussed is CRP; the disease is atrial fibrillation.