Here, we used a variable-sized photothrombotic stroke model that targets the primary forepaw somatosensory cortex (S1FP) in the left hemisphere to produce infarcts of different sizes in conjunction with wide-field calcium imaging in transgenic Thy1-GCaMP mice (expressing a fusion protein of green fluorescent protein and the calcium-binding calmodulin protein under the Thy1 promoter) to examine the effects of infarct size and degree of injury sustained in S1FP on remapping, functional network repair, network dynamics, and behavioral recovery. Here, THY1 is linked to stroke disorder.