HOXC5 and neuroblastoma: RNA sequencing results showed a synergistic induction of genes associated with RA signaling (RARB, RARG), neuronal differentiation (HOXC5, PBX1), and chromatin remodeling (RYBP, JADE2), which are positively correlated with favorable prognosis in neuroblastoma (Fig. 3C, S3C).