Additionally, the 0.3mg/kg, 0.1mg/kg, and 0.03mg/kg LNP-CTNNB1 dosages resulted in partial responses, with remnant microscopic tumor foci observed in 0.3mg/kg and 0.1mg/kg treated animals (Figure S2e) and macroscopic tumor nodules present in animals treated with 0.03mg/kg (Figure S2b, e). Here, CTNNB1 is linked to neoplasm.