WT1-CTLs from all 3 donors tested displayed significant cytotoxicity against the 3 AML cell lines at both low and high effector:target (E:T) ratios, with < 50% of AML cells remaining viable at an E:T of 0.5 and < 10% alive at an E:T of 5 (Fig. 1D, Supplementary Figs. 1E-F). The gene discussed is WT1; the disease is acute myeloid leukemia.