To further analyze the expression of MTAP in tumor cells and its surrounding environment in GBM patients, paraffin‐embedded tissue microarray of human glioma specimens using multiplexed immunofluorescence staining was used to demonstrate MTAP, PRMT5, and microglia (Iba‐1) expression in glioma tissues (Figure 2B). The gene discussed is PRMT5; the disease is central nervous system cancer.