The univariate MR analysis (Figure 2) based on the IVW results suggested that prolonged and heavy use of blood pressure medication (OR: 1.013008 [1.0075447, 1.018501], p < 0.001), cholesterol‐lowering medication (OR: 1.009958 [1.0018371, 1.018144], p = 0.0161449), or insulin (OR: 1.068113 [1.0145236, 1.124532], p = 0.01210576) may elevate the prevalence of cerebral infarction. This evidence concerns the gene INS and cerebral infarction.