Notably, the increased infarct volume detected in Nfat5(EC)−/− mice 24 h upon onset of stroke was not accompanied by an altered degree of apoptosis (Supplement S3A) or degenerating neurons (Supplement S3) across the ipsilateral striatum (infarct core) and cortex (ischemic peri-infarct area; specification of anatomical sub regions is shown in Supplement S2). Here, NFAT5 is linked to Stroke.