The antibody dynamics after SARS-CoV-2 infection varies widely between individuals, with children and asymptomatic patients tending to have lower antibody levels.45–48 For IgG levels, which persist longer than IgM, a significant decline has been reported in children up to 180 days after infection.46 Thus, uncertainty remains regarding the infection rate, which may be slightly higher. The gene discussed is CD40LG; the disease is infection.