In the Malaysian dengue cohort, RNA sequencing of PBMC samples identified a unique set of genes (CCL7, TNFSF15, MYLK2, and SERPINB2) involved with platelet aggregation, inflammation, vascular leakage, and thrombosis as indicators of disease severity in dengue infection (Suppiah et al., 2024 Oct 14). The gene discussed is SERPINB2; the disease is dengue disease.