In a recent large study of genetic contributions to sudden unexpected death in paediatrics (including both SUDC and SUID cases), exome sequencing identified contributory variants in 11% of the cases, including pathogenic variants in epilepsy and cardiac genes such as SCN1A, DEPDC5, GABRG2, SCN5A, TTN, MYBPC3, PLN, and TNNI3.35 The gene discussed is SCN5A; the disease is epilepsy.