Compared to those on DTG, individuals on RAL and DRV had a higher rate of hepatitis B virus infection (9 and 8% vs 6%), hepatitis C virus infection (35 and 27% vs 25%), lower median CD4 count (498 and 434 vs 554 cells/uL), lower proportions being suppressed (69 and 55% vs 74%), higher VACS index 2.0 (51 and 53 vs 49), and more non-ARV co-medications (10 and 9 vs 9). This evidence concerns the gene CD4 and hepatitis B virus infection.