Other genes upregulated in MS CSF compared with either OIND or ID controls included CD99—a mediator of DC migration from tissues into lymph nodes39—in mDCs, CRIP2—an inhibitor of nuclear factor κB signaling40—in CD4+ T cells, and LEKR1—an MS susceptibility locus41—in CD14+ monocytes. Here, LEKR1 is linked to myeloid sarcoma.