In the absence of inflammation—i.e., in the cohort of patients with NINDs such as primary headache syndromes and idiopathic intracranial hypertension—CSF was enriched with dendritic cells (DCs), CD8+ T cells, monocyte-derived CSF macrophages, and regulatory T cells (Tregs, false discovery rate [FDR] < 0.01) and depleted of B cells and monocytes compared with the peripheral blood.7 Here, CD8A is linked to pseudotumor cerebri.