In addition, we investigated the relationship between BEST3 and several key immune checkpoint genes, including CD274, CD276, CD80, CD86, PDCD1 and CTLA4, in NSCLC patients using the UCSCXenaShiny platform (https://shiny.hiplot.cn/ucsc‐xena‐shiny/). The gene discussed is CD276; the disease is non-small cell lung carcinoma.