ACE and chronic kidney disease: The multi-centre randomised controlled trial of Angiotensin-Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Withdrawal in Advanced Renal Disease (STOP-ACEi) found that the discontinuation of RAAS inhibitors was not associated with a significant difference in the long-term rate of decrease in the eGFR in CKD stages 4 to 5 [27].