In accordance, rosuvastatin showed anticoagulant effect in patients with venous thrombosis by increasing LRP1 expression both in vitro and in vivo (Paciullo and Gresele, 2019) and high dose rosuvastatin was required to increase ABCA1 transporter in human atherosclerotic plaques (Santovito et al., 2020). Here, LRP1 is linked to Venous thrombosis.