Several studies have shown that abundantly expressed IL-33 in asthma patients (Prefontaine et al. 2010, Raeiszadeh et al. 2014) and OVA challenge experimental mice model (Louten et al. 2011) and confirmed elevated IL-33 expression in the airway epithelium of asthma patients (Prefontaine et al. 2010). The gene discussed is IL33; the disease is asthma.