Moreover, the high level of serum PTGDS ( > 56.9 ng/mL) was found to be associated with clinical characteristics in PTCL patients, including high IPI score, elevated β2-MG, advanced stage and elevated ESR (Supplementary Fig. S1F, Supplementary Table 3). Here, PTGDS is linked to mature T-cell and NK-cell non-Hodgkin lymphoma.