SDHB and neoplasm: In a PCC/PGL cohort that included 145 patients (8), methylome analysis identified a single tumor carrying noSDHx mutation that displayed a hypermethylator phenotype andhad an ‘SDH-like’ behavior for a prevalence of 0.7%.The tumor was a local recurrence of a PCC resected from a woman presenting with highlevels of urinary normetanephrine.