We found that, compared with patients with low VEGF expression, patients with high VEGF expression had more advanced tumor stage, worse tissue differentiation, and were more likely to have lymph node metastasis, which was consistent with previous research results of Xu et al.[23] These aggressive histopathological features may significantly affect the survival outcomes of patients with cancer. This evidence concerns the gene VEGFA and metastatic malignant neoplasm in the lymph nodes.