Prostate cancer (PCa) is a clinically diverse disease, varying from “insignificant cancers” to “poor-prognosis cancers” that can metastasize and lead to death.[15] Androgens stimulate prostate cancer growth, and treatments often involve reducing androgen activity through chemical or surgical castration or using antiandrogens to block androgen binding to the AR. Here, AR is linked to posterior cortical atrophy.