Jiang et al[9] found that the exosomes lnc RNA OIP5-AS1 original CAF, weakens the inhibitory effect of miR-142-5p on PD-L1 by inhibiting the expression of miR-142-5p, upregulates PD-L1 expression, and inhibits the cytotoxicity of lung cancer cells induced by mononuclear cells. Here, CD274 is linked to lung carcinoma.