PIK3CA and lung carcinoma: Exosomal LINC00662 promote lung cancer proliferation, migration, and invasion by binding to miR-320d.[50] Mao et al[51] found that exosomes rich in FOXD3AS1 activate the PI3K/Akt signaling pathway by interacting with ELAVL1, promoting lung cancer cell proliferation and invasion and thereby promoting tumor progression.