Research found that the expression level of GAS5 in NSCLC patients is lower than that of healthy subjects, which increases the proliferation of tumor cells.[55] Study showed that GAS5 levels are related to TNM staging and tumor size of NSCLC, and serum exosomes GAS5 expression in advanced NSCLC patients is lower than that in early NSCLC patients. The gene discussed is GAS5; the disease is neoplasm.