SLC25A18 and lung cancer: In contrast, individuals with higher 25(OH)D and any Gc2 isoform had a better lung cancer outcome (i.e., no increased risk) compared with individuals with only Gc1 isoforms (higher risk), and even though the interaction was not statistically significant, it was similar in direction to our previous finding of improved lung cancer survival in cases with higher 25(OH)D and any Gc2 isoform [15].