Protein levels of IFN‐γ, IL‐12, CXCR3, CCR5, IL‐4, IL‐5, IL‐13, CCR3, CD40, CD40L, IL‐56 and CD56 were all significantly higher in lesional SS skin samples, vs. HCs (p = < 0.05). The gene discussed is CD40LG; the disease is synovial sarcoma.