The difference in TIIRG expression between IDCM and ICM shows that JAK1 and IFNA16/IFNA14 have a good differentiation effect on these two types of HF; particularly, the model constructed on the basis of these three genes can achieve an AUC of 0.722, and when the model value is < 0.359, most patients belonged to IDCM. This evidence concerns the gene IFNA14 and hydrops fetalis.