SLC17A7 and Alzheimer disease: A decrease in levels of hippocampal and cortical mGluR5, vesicular glutamate transporter 1 (VGLUT1) and other glutamatergic signaling related proteins is correlated with depression-like behaviors in 6xTg and 3xTg-AD mice (Cassano et al., 2012; Kim et al., 2023).