Two remaining studies assessed podocyte nephrin+ MVs and diabetic retinopathy (AUC: 0.899) and the combination of uracil, LPC (O-18:1/0:0), S1P, and 4-acetamido butyric acid (AUC: 0.944) as diagnostic biomarkers of DKD (23, 41). Here, NPHS1 is linked to diabetic retinopathy.