It showed anti-inflammatory and tumor-promoting proteins and hypoxia-associated proteins, metabolites induced upon hypoxia (whereas metabolites in pro-inflammatory pathways had the same low abundance in control and medulloblastoma samples), and an anti-inflammatory epoxygenase product and beta-oxidation promoting lipid hormone called 12,13-DiHOME, which were more abundant in medulloblastoma samples. Here, SPRR2A is linked to medulloblastoma.