Our findings indicate that, while there were no significant differences in infarct size between WT and Crlf2-/- mice at 1 day after MI, Crlf2-/- mice exhibited a larger and thinner infarct scar at 28 days post-MI (Figures 3A–C, Supplementary Figures S3B, C). Here, CRLF2 is linked to myocardial infarction.