Immunohistochemical staining showed the tumor cells to be negative for CK7, CK20, ALK, HMB45, melanin A, 2SC, TTF1, calretinin, ER, p53 (wild type), and WT1, and positive for AMACR, PAX8, AE1/AE3 (focal), CAIX (rare/focal), CD10, vimentin, AR, and fumarate hydratase. The gene discussed is CA9; the disease is neoplasm.