Seven lncRNAs (ABHD11‐AS1, CASC15, HCG18, LINC00494, LINC00665, LINC00992, and TMEM51‐AS1) were found to be affected by ECM stiffness, and their RNA levels increased in ICC cells on the 16 kPa plates (Figure 3B; n = 3). This evidence concerns the gene CASC15 and intrahepatic cholangiocarcinoma.