Importantly, the model fulfils the key criteria of the fourth universal definition of MI, demonstrating: (1) the rise and fall of a cardiac biomarker (cTni); (2) ECG changes in the ST‐T segment; (3) ECG evidence of wall motion abnormality; and (4) evidence of scar/infarct on the heart. The gene discussed is TNNI3; the disease is myocardial infarction.