Moreover, LRH‐1/NR5A2 activation also imposes an anti‐inflammatory and regenerative phenotype on naïve T1D M10 and iDCs, as assessed by increased secretion of the pro‐angiogenic cytokines ANG and CCL4 in M10 and decreased secretion of the anti‐angiogenic factor HGF in iDCs, further limiting the recruitment/activation of additional M1 and mDCs. Here, CCL4 is linked to type 1 diabetes mellitus.