The most up‐regulated DEP, SPTBN1, was shown to inhibit inflammatory responses and hepatocarcinogenesis in hepatocellular carcinoma via down‐regulation of the NF‐κB signalling pathway, which was also suppressed in T1D M168 (Figure 3B,G, black arrow and Figure 2D). Here, NFKB1 is linked to type 1 diabetes mellitus.