Subsequently, several other genes associated with sarcoma, intestinal cancer, kidney cancer and breast cancer (APC, MUTYH, MSH2, MLH1, MSH6, PMS2, STK11, SMAD4, BMPR1A, PTEN, TP53, CDH1, PALB2, RAD51C, RAD51D, SDHB, SDHC, SDHD, and VHL) were analysed, and an APC gene (NM_000038.6) variant (c.3920T > A, p.(Ile1307Lys) was detected. The gene discussed is APC; the disease is intestinal cancer.