Variants in the gene encoding 12S rRNA (MT-RNR1, MIM: 561000) are associated with sensorineural, non-syndromic deafness,49 suggesting that, as a result of their reduced abundance, altered MRPS7 and 12S rRNA interactions might account for the SNHL in individuals with variants in DAP3. Here, MRPS7 is linked to deafness.