LRRK2 and Parkinson disease: Nonsynonymous sequence variants within the Leucine-Rich Repeat Kinase 2 (LRRK2) are associated with familial forms of Parkinson’s disease (PD) and are phenotypically indistinguishable from idiopathic forms of PD (iPD) (Paisán-Ruíz et al., 2004; Zimprich et al., 2004).