In addition, the polymorphism Arg399Gln of the XRCC1 gene with the risk of developing colorectal cancer in the study by Kabzinski et al. [17] revealed that Arg/Gln (T/C) genotype increased the risk of colorectal cancer (OR ═ 2.481, 95% confidence interval [CI]: 1.745–3.529, P < 0.0001). The gene discussed is XRCC1; the disease is colorectal cancer.