59 Ding Ding JF JF Sun Sun H H Song Song K K Zhou Zhou Y Y Tu Tu B B Shi Shi KH KH et al et al IGFBP3 Epigenetic Promotion Induced by METTL3 Boosts Cardiac Fibroblast Activation and Fibrosis IGFBP3 Epigenetic Promotion Induced by METTL3 Boosts Cardiac Fibroblast Activation and Fibrosis Eur J Pharmacol Eur J Pharmacol 2023 2023 942 942 175494 175494 10.1016/j.ejphar.2023.175494 10.1016/j.ejphar.2023.175494. The gene discussed is METTL3; the disease is fibrosis.