Using a regimen of 100 mg/kg every 2 hours for ATM and AVI used in combination, the percentages of fT>MIC (ATM) and fTCT>2.5 mg/L (AVI) were 100% and 72.9%, close to those obtained in humans at dosages recommended for severe infections (98.0% and 70.3%, respectively) (13) (Table 2). Here, ATM is linked to infection.