Recently, G protein-coupled receptor 84 (GPR84) has emerged as a potentially importantplayer in the context of AML.40 While its precise role in AMLpathogenesis is still being studied, evidence suggests that GPR84 may be crucial inpromoting leukemic cell survival, proliferation, and chemoresistance.40The activation of GPR84 is thought to influence the expression of genes associated withcellular processes such as cell cycle regulation, apoptosis, and inflammation. The gene discussed is GPR84; the disease is acute myeloid leukemia.