KLK3 and posterior cortical atrophy: The benefit of using PSAD over PSA is that it accounts for enlarged prostates naturally increasing PSA levels in the blood, which alone is not necessarily a sign of PCa.\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{upgreek}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}\begin{equation*}PSAD = \frac{{PSA}}{{PV}} \tag{1}\end{equation*}\end{document}