MITF and melanoma: Nonetheless, despite large interpatient variability (Supplementary Figure S4, available at https://doi.org/10.1016/j.iotech.2024.101009) characterizing the changes of the four phenotypic melanoma cell subsets within the melanoma cell population, we observed a significant decrease in AXL− MITF+ melanoma cells (P = 0.0494) and a trend toward an increase in AXL+ MITF− melanoma cells upon treatment (P = 0.0580, Figure 3D).