Preoperative investigations did not show elevation of tumor markers (lactate dehydrogenase (LDH) 140 U/L, carcinoembryonic antigen (CEA) 0.7 ng/mL, cancer antigen (CA) 19-9 5.1 U/mL, CA125 5.7 U/mL, alpha-fetoprotein (AFP) 1.1 ng/mL, squamous cell carcinoma (SCC) 1.4 ng/mL, neuron-specific enolase (NSE) 8.7 ng/mL) or abnormal findings in vaginal stump cytology. The gene discussed is ENO2; the disease is neoplasm.